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Early-stage trial tests MAb with docetaxel
November 15, 2013
By: Gil Roth
President, Pharma & Biopharma Outsourcing Association
OncoMed Pharmaceuticals has started a multi-center Phase Ib trial of its first-in-class Wnt-pathway-targeting antibody vantictumab (OMP-18R5) with docetaxel in non-small cell lung cancer (NSCLC). This trial is the second of three Phase Ib trials for vantictumab that OncoMed expects to initiate this year as part of the company’s collaboration with Bayer Pharma AG. The trial is a dose-escalation study of the anti-CSC antibody vantictumab in combination with docetaxel in patients with second...
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